Antiradical and antioxidant activity of the extracts three kinds of medicinal plants and Lemna minor L.

The effectiveness of the antiradical and antioxidant effects of extracts of Phlojodicarpus sibiricus Steph. ex Spreng., Rhodiola rosea L., Rhodiola borealis Boriss and Lemna minor were study. The antioxidant activity of root extracts was investigated depending on the concentration of the extractant (40 and 70 % water-ethanol mixtures). The anti-radical activity of all extracts against DPPH and ABTS+ radicals was 90–99 %, regardless of the organs used and the concentration of extractants. The most effective in the models of superoxide-radical scavenging were extracts of the roots of R. borealis, R. rosea, as well as extracts of the aerial organs of R. rosea and callus P. sibiricus. All studied extracts of P. sibiricus and R. rosea had a high level of inhibition of NO-radicals. The extracts of R. rosea of the Yakut population exceeded the commercial preparation of R. rosea and extracts of R. borealis by the scavenging of NO radicals. In models of induced LPO, a high efficiency of inhibiting free radical oxidation was observed in 40 % of root extracts of R. rosea (54–59 %) and R. borealis, P. sibiricus (34–36 %). By comparing the antiradical and antioxidant activity of the extracts, depending on the concentration of the extractant, the greatest efficiency of radical scavenging with 40 % water-ethanol extracts was established. The possibility of considering the extracts of the studied plants as promising means of reducing the free radical load caused by oxidative stress is shown. It was noted that the antioxidant activity of extracts from the roots and aerial parts of rosea, P. sibiricus and its callus was comparable with commercial preparations of the roots of R. rosea and ginseng, and also exceeded them in relation to the inhibition of certain types of free radicals.

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