resarПриродные ресурсы Арктики и СубарктикиArctic and Subarctic Natural Resources2618-97122686-9683Академия наук Республики Саха (Якутия)10.31242/2618-9712-2022-27-4-610-617resar-82Research ArticleОбщая биология. Биологические ресурсыGeneral biology. Biological resourcesПерспективность рационального использования биологически активных веществ из хвои Pinus sylvestris для создания биопрепаратовThe prospects for the rational use of biologically active substances from Pinus sylvestris needles in the creation of biopreparationshttps://orcid.org/0000-0003-4498-7743МихайловВ. В.MikhailovV. V.

МИХАЙЛОВ Владислав Васильевич, инженер-исследователь, Author ID: 57290621700, Researcher ID: AAC-2800-2022

677980, г. Якутск, пр. Ленина, 41

MIKHAILOV, Vladislav Vasilevich, Research Engineer, Author ID: 57290621700, Researcher ID: AAC-2800-2022

41 Lenin pr., Yakutsk 677980

nethrezim@mail.ruhttps://orcid.org/0000-0002-5980-579XСлепцовИ. В.SleptsovI. V.

СЛЕПЦОВ Игорь Витальевич, кандидат биологических наук, старший научный сотрудник, Author ID: 57200540770, Researcher ID: J-7736-2018

677980, г. Якутск, пр. Ленина, 41

SLEPTSOV, Igor Vitalevich, Senior Researcher, Cand. Sci. (Biology), Author ID: 57200540770, Researcher ID: J-7736-2018

41 Lenin pr., Yakutsk 677980

neroxasg@mail.ruhttps://orcid.org/0000-0001-7223-9297РожинаС. М.RozhinaS. M.

РОЖИНА Сахаяна Михайловна, младший научный сотрудник, Author ID: 57208332809, Researcher ID: AAO-3383-2020

677980, г. Якутск, пр. Ленина, 41

ROZHINA, Sakhayana Mikhaylovna, Junior Researcher, Author ID: 57208332809, Researcher ID: AAO-3383-2020

41 Lenin pr., Yakutsk 677980

ahayana-rozhina@mail.ruhttps://orcid.org/0000-0001-8823-3981КершенгольцБ. М.KershengoltsB. M.

КЕРШЕНГОЛЬЦ Борис Моисеевич, доктор биологических наук, главный научный сотрудник, профессор, Author ID: 55604639100

677980, г. Якутск, пр. Ленина, 41

KERSHENGOLTS, Boris Moiseevich, Chief Researcher, Dr. Sci. (Biology), Professor, Author ID: 55604639100

41 Lenin pr., Yakutsk 677980

kershen@mail.ruИнститут биологических проблем криолитозоны СО РАНРоссияInstitute for Biological Problems of Cryolithozone, Siberian Branch of the Russian Academy of SciencesRussian Federation202209092022274610617Copyright © Михайлов В.В., Слепцов И.В., Рожина С.М., Кершенгольц Б.М., 20222022Михайлов В.В., Слепцов И.В., Рожина С.М., Кершенгольц Б.М.Mikhailov V.V., Sleptsov I.V., Rozhina S.M., Kershengolts B.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://resar.elpub.ru/jour/article/view/82

Проведено исследование годовой динамики накопления метаболитов в хвое обыкновенной сосны (Pinus sylvestris L.), произрастающей на территории Центральной Якутии. Установлено, что в хвое сосны содержатся ценные биоактивные вещества, эффективные при профилактике и купировании нарушений обмена веществ, возникающих при сахарном диабете 2-го типа и при формировании других метаболических нарушений, связанных с гиперхолестеринемией, а также вещества криопротекторного действия. Показано, что наибольшие содержания антиоксидантов, таких как галловая, бензойная, аминомасляная кислота, наблюдаются осенью, также в этот период возрастает содержание полиолов, аминокислот и углеводов. На основании полученных данных выдвинуто предположение о том, что в целях создания биопрепаратов, нормализующих углеводный обмен, а также защищающих кожные покровы от действия низких температур, рационально использовать в качестве сырья хвою P. sylvestris, отобранную осенью.

In this article we present the research results of a year-round accumulation dynamics of the metabolites in the needles of Scots pine (Pinus sylvestris L.) growing in Central Yakutia. Pine needles contain valuable bioactive substances effective for preventing and curing metabolic disorders in diabetes mellitus type 2 and the formation of other metabolic disorders associated with hypercholesterolemia. They also contain substances with cryoprotective properties. The highest content of antioxidants in the Pinus sylvestris L. (gallic acid, benzoic acid, aminobutyric acid) were observed in autumn. Moreover, the content of polyols, amino acids and carbohydrates increased in them during this period. Thus, we suppose it is rational to the use P. sylvestris needles gathered in autumn to produce biopreparations for normalizing carbohydrate metabolism or protecting skin from the effects of low temperatures.

Pinus sylvestrisбиопрепаратыпротиводиабетическое действиехолодовая защитаPinus sylvestrisbiopreparationsantidiabetic effectfrostbite protectionРабота выполнена в рамках госзадания Министерства науки и высшего образования РФ России по проекту «Физиолого-биохимические механизмы адаптации растений, животных, человека к условиям Арктики/Субарктики и разработка биопрепаратов на основе природного северного сырья, повышающих эффективность адаптационного процесса и уровень здоровья человека в экстремальных условиях среды» (тема № 0297-2021-0025, ЕГИСУ НИОКТР № АААА-А21-121012190035-9), НИР «Разработка и внедрение в практическое здравоохранение биогенных методов повышения уровня здоровья и адаптивного потенциала организма человека, его умственной и физической работоспособности в экстремальных условиях природной и социальной среды путем создания биопрепаратов из тканей северных экоформ растений и аборигенных видов животных. 2 этап» (Государственный контракт № 535) и с применением оборудования ЦКП ФИЦ «ЯНЦ СО РАН» (грант № 13.ЦКП.21.0016).This study was carried out within the State Assignment of the Ministry of Science and Higher Education of the Russian Federation (theme number 0297-2021-0025, reg. number АААА-А21-121012190035-9); the Research project “Development and implementation in practical health care of biogenic methods to improve health and adaptive capacity of the human body, its mental and physical performance in extreme conditions of natural and social environment by creating biopreparations from tissues of the northern ecoforms of plants and indigenous animal species. 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The authors declare that there are no conflicts of interest present.